Astera Institute
AI

Research Scientist Engineer TwoPhoton Imaging Holographic Optogenetics

Astera Institute · CA, US · $180k - $230k

Actively hiring Posted about 2 hours ago

Role overview

Astera Neuro is a neuroscience research company building the tools and infrastructure required to understand how the brain works at scale. We develop cutting-edge hardware and recording systems, with the goal of enabling the next generation of discoveries about neural circuits, cognition, and behavior.

Compensation Range: $180K - $230K

What you'll work on

  • Perform stereotaxic rodent surgeries: AAV viral vector delivery, chronic cranial window implantation, and GRIN lens or miniscope head-mount installation in mice and rats.
  • Design, build, and iterate on a miniaturized two-photon microscope incorporating spatial light modulators for holographic photostimulation.
  • Develop and optimize two-photon optogenetics protocols for single-cell and ensemble-level activation with minimal off-target excitation.
  • Lead computational analysis of large-scale neural population data, including dimensionality reduction, population decoding, generalized linear models, and circuit-level inference.
  • Collaborate with optical engineers, software developers, and neuroscientists to integrate hardware, software, and biology into a coherent experimental platform.
  • Contribute to publications and internal technical documentation.

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