Promega Corporation
AI

Sr Research Scientist 1

Promega Corporation · Madison, WI, US

Actively hiring Posted about 22 hours ago

Role overview

As a Senior Research Scientist on the Drug Discovery Technologies team, you will work at the intersection of assay development and computational biology, helping us design smarter experiments, generate richer datasets, and engage more deeply with customers and collaborators who are building next-generation drug discovery pipelines. You will design and execute cell-based and biochemical assays to characterize induced proximity compounds, generate multiparametric datasets suited for AI-driven analysis, and apply computational tools to extract actionable insights from complex biological data. You will engage directly with customers to understand their needs and translate those insights into development priorities, contribute to impactful collaborations, and present your work at scientific conferences and in publications.

What you'll work on

  1. Becomes a technical expert in the application of Promega technologies to induced proximity pharmacology and targeted protein degradation. Assumes a leading role in developing new products and research directions that address the emerging needs of AI-guided drug discovery workflows.

  2. Leads hypothesis-driven experimental design, execution, data analysis, and troubleshooting to generate multiparametric, high-quality datasets suitable for computational and machine learning applications.

  3. Develops and applies computational and predictive modeling approaches to support assay design, data interpretation, and product concept iteration. Translates computational outputs into actionable experimental and product decisions.

  4. Contributes to the design and development of an automated drug discovery laboratory, embedding AI-driven biology capabilities into Promega's broader R&D infrastructure.

  5. Generates clear and concise technical documentation and contributes to internal reports and external scientific literature.

  6. Fosters strong relationships through effective communication and presentation to internal project teams and external customers or collaborators.

  7. Stays current on relevant industry technologies, methodologies, and trends in induced proximity pharmacology, chemical biology, and AI-driven drug discovery, and implements new techniques as appropriate.

  8. Works independently; may mentor, direct, or serve as a technical resource for the work of others.

  9. Demonstrates inclusion through their own words and actions and is accountable for a safe workspace. Acts with kindness, curiosity and respect for others.

  10. Embraces and is open to incorporating Promega’s 6 Emotional & Social Intelligence (ESI) core principles in daily work.

  11. Understands and complies with ethical, legal and regulatory requirements applicable to our business.

What we're looking for

  1. Background in chemical biology, drug discovery, or pharmacology, with exposure to proximity-based or protein interaction modalities a plus.

  2. Familiarity with luminescence- or fluorescence-based detection methods in a cell biology or biochemical assay context.

  3. Familiarity with high-throughput screening (HTS) workflows or experience working in an environment where HTS approaches are applied.

  4. Track record of scientific publication or external presentation.

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