Huberman Lab
Huberman Lab

Essentials: Compulsive Behaviors & Deep Brain Stimulation | Dr. Casey Halpern

07 May 2026 38:06 Scicomm Media

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About this episode

In this Huberman Lab Essentials episode, my guest is Dr. Casey Halpern, MD, a professor of neurosurgery at the Perelman School of Medicine at the University of Pennsylvania. We discuss how deep brain stimulation and other neuromodulation approaches are being used to treat Parkinson's disease, obsessive-compulsive disorder (OCD), binge eating disorder and depression-related symptoms. We also explore the brain circuits that drive compulsions, cravings and impulsivity, as well as emerging non-invasive tools for predicting and treating harmful behaviors.

Read the episode show notes at hubermanlab.com.

Thank you to our sponsors

AG1: https://drinkag1.com/huberman

Function: https://functionhealth.com/huberman

Rorra: https://rorra.com.huberman

Timestamps

(00:00:00) Casey Halpern

(00:00:20) Neurosurgery, Deep Brain Stimulation

(00:04:19) Obsessive-Compulsive Disorder (OCD) & Treatments

(00:10:11) Sponsor: Function

(00:11:49) OCD Brain Areas, Addiction

(00:14:12) Nucleus Accumbens, Risk & Rewards; Binge Eating Disorder

(00:18:28) Sponsor: AG1

(00:19:46) Non-Invasive Brain Stimulation, Transcranial Magnetic Stimulation

(00:27:31) Sponsor: Rorra

(00:28:46) Awareness of Cravings, Severe Binge Eating Disorder

(00:32:51) Artificial Intelligence/Machine Learning & Predicting Impulsive Behavior

(00:36:57) Acknowledgements

Disclaimer & Disclosures

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